by David Wallace, Founder, PV Reporter & MPN Cancer Connection When I was first diagnosed with polycythemia vera, nobody told me that PV remission was even possible. And the only treatment I was given, phlebotomy alone, guaranteed it wouldn’t be. Today, my blood counts are normal and the molecular markers driving my PV are undetectable. […]
One Pill, Once a Day: FDA Approves Jakafi XR
Summary Ruxolitinib, the cornerstone treatment for myelofibrosis, polycythemia vera, and graft-versus-host disease, just got easier to take. On May 1, 2026, the FDA approved Jakafi XR™, a once-daily extended-release tablet formulation of the same proven drug. It will be available at pharmacies as early as May 8. Key Points Same medicine, simpler schedule: Jakafi XR […]
Interferon Treatment for MPNs: What You Need to Know
by David Wallace The Big Picture If you’ve been diagnosed with a myeloproliferative neoplasm (MPN) such as polycythemia vera, essential thrombocythemia, or myelofibrosis, you’ve likely heard about interferon therapy. Keep reading to discover what current research tells us about this treatment option. What Exactly Is Interferon? Think of interferon as your body’s natural antiviral security […]
Beta-Alanine for PV Related Itching: A Potential Solution
by David Wallace For many people living with polycythemia vera (PV) and other myeloproliferative neoplasms, stepping into a warm shower can trigger an unbearable sensation that has nothing to do with the water temperature. Aquagenic pruritus (intense itching that occurs after contact with water) remains one of the most frustrating symptoms patients face, affecting nearly […]
Polycythemia Vera Brain Fog
by David Wallace updated July 10, 2025 This is no wonderful “epiphany moment” article, just a quick report on a real myeloproliferative neoplasm (MPN) symptom I experience from time to time. Many mornings, I make a healthy smoothie to get me up and rolling. This morning I grabbed the wrong ingredient and sprinkled it in […]
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