Summary Ruxolitinib, the cornerstone treatment for myelofibrosis, polycythemia vera, and graft-versus-host disease, just got easier to take. On May 1, 2026, the FDA approved Jakafi XR™, a once-daily extended-release tablet formulation of the same proven drug. It will be available at pharmacies as early as May 8. Key Points Same medicine, simpler schedule: Jakafi XR […]
Remembering Dr. Richard T. Silver (1929–2026): MPN Pioneer
by David Wallace Dr. Richard T. Silver died on April 17, 2026, at the age of 97. He was born on January 18, 1929. In the 97 years between those two dates, he built a career that is difficult to summarize without sounding like a highlight reel, and yet every line of it is true. […]
Interferon for Myelofibrosis: 2025 Study Challenges “Watch and Wait”
by David Wallace For years, the medical community has told us the same thing when we’re diagnosed with early-stage myeloproliferative neoplasms: “Let’s watch and wait.” The thinking was straightforward: why expose someone to treatment side effects when they’re not yet symptomatic? But a study published this December in the journal Cancers is challenging that entire […]
GLP-1 Therapies May Benefit MPN and MDS Patients
by David Wallace The treatment landscape for type 2 diabetes and obesity has changed dramatically with the rise of GLP-1 therapies. If you’ve been following medications like Ozempic, Wegovy, or Zepbound (tirzepatide), you know they belong to a class of drugs called glucagon-like peptide-1 receptor agonists (GLP-1 RAs). These drugs mimic the natural hormone GLP-1, […]
Interferon Treatment for MPNs: What You Need to Know
by David Wallace The Big Picture If you’ve been diagnosed with a myeloproliferative neoplasm (MPN) such as polycythemia vera, essential thrombocythemia, or myelofibrosis, you’ve likely heard about interferon therapy. Keep reading to discover what current research tells us about this treatment option. What Exactly Is Interferon? Think of interferon as your body’s natural antiviral security […]
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