Summary Ruxolitinib, the cornerstone treatment for myelofibrosis, polycythemia vera, and graft-versus-host disease, just got easier to take. On May 1, 2026, the FDA approved Jakafi XR™, a once-daily extended-release tablet formulation of the same proven drug. It will be available at pharmacies as early as May 8. Key Points Same medicine, simpler schedule: Jakafi XR […]
Remembering Dr. Richard T. Silver (1929–2026): MPN Pioneer
by David Wallace Dr. Richard T. Silver died on April 17, 2026, at the age of 97. He was born on January 18, 1929. In the 97 years between those two dates, he built a career that is difficult to summarize without sounding like a highlight reel, and yet every line of it is true. […]
Interferon for Myelofibrosis: 2025 Study Challenges “Watch and Wait”
by David Wallace For years, the medical community has told us the same thing when we’re diagnosed with early-stage myeloproliferative neoplasms: “Let’s watch and wait.” The thinking was straightforward: why expose someone to treatment side effects when they’re not yet symptomatic? But a study published this December in the journal Cancers is challenging that entire […]
GLP-1 Therapies May Benefit MPN and MDS Patients
by David Wallace The treatment landscape for type 2 diabetes and obesity has changed dramatically with the rise of GLP-1 therapies. If you’ve been following medications like Ozempic, Wegovy, or Zepbound (tirzepatide), you know they belong to a class of drugs called glucagon-like peptide-1 receptor agonists (GLP-1 RAs). These drugs mimic the natural hormone GLP-1, […]
Interferon Treatment for MPNs: What You Need to Know
by David Wallace The Big Picture If you’ve been diagnosed with a myeloproliferative neoplasm (MPN) such as polycythemia vera, essential thrombocythemia, or myelofibrosis, you’ve likely heard about interferon therapy. Keep reading to discover what current research tells us about this treatment option. What Exactly Is Interferon? Think of interferon as your body’s natural antiviral security […]
Beta-Alanine for PV Related Itching: A Potential Solution
by David Wallace For many people living with polycythemia vera (PV) and other myeloproliferative neoplasms, stepping into a warm shower can trigger an unbearable sensation that has nothing to do with the water temperature. Aquagenic pruritus (intense itching that occurs after contact with water) remains one of the most frustrating symptoms patients face, affecting nearly […]
Polycythemia Vera Brain Fog
by David Wallace updated July 10, 2025 This is no wonderful “epiphany moment” article, just a quick report on a real myeloproliferative neoplasm (MPN) symptom I experience from time to time. Many mornings, I make a healthy smoothie to get me up and rolling. This morning I grabbed the wrong ingredient and sprinkled it in […]
Breakthrough CALR Therapy Shows High Response Rate in ET
by David Wallace New Treatment Targets Root Cause of ET: INCA033989 Trial Shows Powerful Results June 15, 2025 – EHA Congress, Milan Incyte has announced positive, late-breaking data from the first clinical studies of its experimental therapy INCA033989—an antibody designed to precisely target a genetic driver of disease in patients with Essential Thrombocythemia (ET). The […]
Rusfertide Cuts Phlebotomies by 77% in Polycythemia Vera
by David Wallace Key Points Rusfertide achieved clinical response in 77% of patients compared to 33% with placebo in the Phase 3 VERIFY trial The drug significantly reduced the number of blood draws needed each year and decreased PV-related symptoms Rusfertide maintained hematocrit levels below 45% and reduced or eliminated the need for phlebotomy Safety […]
Help advance Myelofibrosis research from home
PV Reporter, in partnership with Sanguine Biosciences, is reaching out to raise awareness about an at-home research opportunity for patients diagnosed with Myelofibrosis. What is the goal of the at-home research? The goal of this research is to enhance their understanding of Myelofibrosis, in support of developing new diagnostic and treatment options for patients living […]
- 1
- 2
- 3
- …
- 22
- Next Page »