Myelofibrosis A Phase 2 Study of the Safety, Tolerability, and Efficacy of INCB050465 in Combination With Ruxolitinib in Subjects With Myelofibrosis The purpose of this study is to evaluate the safety, tolerability, and efficacy of the combination of INCB050465 and ruxolitinib in subjects with myelofibrosis Talk to your doctor if you are interested in participating […]
Health Benefits of Therapeutic Oncology Massage for MPN Cancer patients
First in a Series – “Natural Healing Ideas for MPN patients” by David Wallace A Personal Perspective Over the years, I have enjoyed a good massage on rare occasion. An intense week of maneuvering the challenging slopes in Alta, Deer Valley and Snowbird, Utah comes to mind, about 15 years ago (pre-PV). After 3 or […]
David Wallace, PV Reporter honored with 2016 Cure Magazine MPN Hero Award
Our Third Year attending the MPN Heroes Program by David Wallace For the past 4 years, Cure Magazine and Incyte Corporation have recognized leaders within the MPN community with the MPN Hero award. The two categories include commitment to the individual or community. I am honored to receive this award for “commitment to the broader […]
Kickboxing my way to Sunshine!
by Christine Kennedy Happy new year. I hope everyone will be in their best place this year. This disease has a depression end and numbers have a deep hold on us. Last year, physically and mentally, was my best year. Exercise Beats Exhaustion I started kickboxing. I think my body needed exercise. Giving in to […]
MPN Focus Fall2016 – MD Anderson Newsletter – Itching Tips, PV Reporter
The Zyrtec and Zantac combo is helping MPN patients get relief from Itching! Note: Download PDF is a small icon on the top of the gray title bar, just below.
Seven Gene Signature Depicts the Biochemical Profile of Early Prefibrotic Myelofibrosis
Click here for link to original publication. Note: At the bottom of each PDF page, be sure to click on the arrow (bottom left corner) to proceed to the next page. Copyright: c2016 Skov et al. This is an open source article distributed under the terms of the creative commons attribution license, which permits unrestricted […]
Mast Cells and Histamine in MPN Related Itching Explained
2023 Update Pepcid is one of the preferred options (H2 blocker) in combination with Zyrtec (H1 blocker) to combat itching in MPNs. This change was necessary since Zantac was taken off the market due to concerns that it contained dangerous levels of N-Nitrosodimethylamine (NDMA). NDMA is classified as a “probable human carcinogen.” Carcinogens are substances that […]
Over the Counter Combo of Zyrtec and Zantac helping PV patients get relief from Itching!
Part 1 in a New Series: “Addressing MPN Symptoms” by David Wallace 2024 Update Polycythemia vera patients suffering from intense itching have long relied on a combination of over-the-counter medications for relief, commonly known as the “Z and Z combo” – Zyrtec (cetirizine) and Zantac (ranitidine). However, in 2020, Zantac faced a widespread recall due […]
A thrombopoietin receptor antagonist is capable of depleting MF hematopoietic stem and progenitor cells
The following abstract involved the work of Dr Ron Hoffman, the principle investigator (PI), senior member of the MPN group at Mt Sinai Hospital in New York City as well as the PI of the MPN-RC. Xiaoli Wang, Phd, performed all of the lab work. Dr John Mascarenhas was my point of contact for this […]
Heidi’s MPN Story – An Increasing Trend in Patient Advocacy
by Heidi Cascarano “Watch and Wait…” What other cancer, in the 21st century, is so misunderstood that your local doctor will struggle to diagnose you, possibly tell you he has a few other patients with it, then advise you to do nothing but get a therapeutic phlebotomy and take a baby aspirin? You get online […]
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