Geron Announces Fast Track Designation Granted to Imetelstat for Relapsed/Refractory Myelofibrosis MENLO PARK, Calif., Sept. 30, 2019 (GLOBE NEWSWIRE) — Geron Corporation (Nasdaq: GERN) today announced that the United States Food and Drug Administration (FDA) has granted Fast Track designation to imetelstat for the treatment of adult patients with Intermediate-2 or High-risk myelofibrosis (MF) whose […]
05: Tips to Living Well with an MPN
MPN Chronicles Podcast – 05, Tips to healthy living with a Myeloproliferative Neoplasm by David Wallace It’s important for us, as patients to do everything we can naturally to help our body fight MPNs. Here are a few tips: • Eating right, a balanced diet is especially important if you have an MPN as eating […]
MPNs and Insomnia: Tips for Better Sleep
65% of MPN, Cancer Patients report Insomnia, Sleep Problems by Heidi Cascarano Many people struggle with sleep disturbances, and we all know that lack of quality sleep can lead to daytime fatigue, diminished quality of life, and other health problems. What’s worse is that the effects of poor quality sleep can, in turn, further disrupt […]
Inrebic (Fedratinib) receives FDA Approval for Myelofibrosis
The First New Treatment in Nearly a Decade for MF Patients INREBIC provides new, once-daily oral option for patients affected by rare bone marrow cancer SUMMIT, N.J.–(BUSINESS WIRE)–Celgene Corporation (NASDAQ: CELG) today announced the U.S. Food and Drug Administration (FDA) has approved INREBIC® (fedratinib) for the treatment of adult patients with intermediate-2 or high-risk primary or […]
Chronic Pain in Over 50 percent of MPN Cancer patients
Part 4 in a New Series: “Addressing MPN Symptoms” Prevalence of Chronic Pain and High-Impact Chronic Pain in Cancer Survivors in the United States Jiang C, Wang H, Wang Q, Luo Y, Sidlow R, Han X. Prevalence of Chronic Pain and High-Impact Chronic Pain in Cancer Survivors in the United States. JAMA Oncol. Published online June […]
Targeted therapies for Myeloproliferative Neoplasms MPNs
Abstract The discovery of JAK2V617F and the demonstration that BCR-ABL-negative myeloproliferative neoplasms (MPNs) are driven by abnormal JAK2 activation have led to advances in diagnostic algorithms, prognosis and ultimately also treatment strategies. The JAK 1/2 inhibitor ruxolitinib was a pivotal moment in the treatment of MPNs, representing the first targeted treatment in this field. Despite a […]
Nutrition and Diet May Reduce Chronic Inflammation while Improving Symptom Burden in MPN Patients
Part 3 in a New Series: “Addressing MPN Symptoms” Check out the entire series (2022 update) Over the Counter Combo of Zyrtec and Zantac helping PV patients get relief from itching Polycythemia Vera Brain Fog Nutrition and Diet May Reduce Chronic Inflammation while Improving Symptom Burden in MPN patients Chronic Pain in Over 50 percent […]
What I Learned from going through Stem Cell Transplant for Myelofibrosis
No Time Like the Present – To Kick Cancer’s Butt by Heidi Cascarano It wasn’t in the plans. I had lived with the diagnosis of Polycythemia Vera, and then Myelofibrosis for 9 years. I was told I could live several years with them and that progression was the exception. My hope was amplified by my […]
Ten Year Anniversary Living with Polycythemia Vera Blood Cancer
Inspire by Living! by David Wallace Your numbers do NOT always reflect how you feel, so important to remember! I’ve felt like crap before and my numbers were good. How you feel is one of the most important measurement criteria, in my opinion. Counts were off on my last heme visit, about a month ago, […]
Polycythemia Vera Brain Fog
Part 2 in a New Series: “Addressing MPN Symptoms” by David Wallace This is no great “epiphany moment” article, just a quick report on a real myeloproliferative neoplasm (MPN) symptom I experience from time to time. Most mornings, I make a healthy smoothie to get me up and rolling. This morning I grabbed the wrong […]
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