Thrombotic Risk Reduction and High Rate of Complete Molecular Response with the Long Term Use of Ropeg interferon Alpha-2b in Polycythemia Vera: Results from a Randomized Controlled Study, ASH 2019 interview with Dr. Kiladjian by David Wallace Dr. Jean Jacques Kiladjian, Professor of Clinical Hematology, Hopital Saint-Louis, Paris, France interviews with David Wallace, PV Reporter […]
David Wallace Attends MPN Horizons 2019, 4th Annual Global Conference
4th year in Attendance by David Wallace On October 25th, 2019 approximately 50 MPN advocates representing over 25 advocacy groups from around the world met in Lisbon, Portugal for 3 days. The objective was to share best practices of support and advocacy activities, learn about new MPN research and discuss issues that patients in each […]
Zantac Recall Expands, New Options help PV patients calm Itching
MPN Patients have multiple Over The Counter options to relieve Itching! by Jennifer Acker For many PV patients the combination of Zantac (an H2 blocker) and Zyrtec (an H1 blocker) have been effective in providing relief from pruritus, a severe itching condition that is a common MPN symptom. PV Reporter first uncovered this impressive treatment […]
Geron Granted Fast Track Designation on Imetelstat for MF
Geron Announces Fast Track Designation Granted to Imetelstat for Relapsed/Refractory Myelofibrosis MENLO PARK, Calif., Sept. 30, 2019 (GLOBE NEWSWIRE) — Geron Corporation (Nasdaq: GERN) today announced that the United States Food and Drug Administration (FDA) has granted Fast Track designation to imetelstat for the treatment of adult patients with Intermediate-2 or High-risk myelofibrosis (MF) whose […]
05: Tips to Living Well with an MPN
MPN Chronicles Podcast – 05, Tips to healthy living with a Myeloproliferative Neoplasm by David Wallace It’s important for us, as patients to do everything we can naturally to help our body fight MPNs. Here are a few tips: • Eating right, a balanced diet is especially important if you have an MPN as eating […]
MPNs and Insomnia: Tips for Better Sleep
65% of MPN, Cancer Patients report Insomnia, Sleep Problems by Heidi Cascarano Many people struggle with sleep disturbances, and we all know that lack of quality sleep can lead to daytime fatigue, diminished quality of life, and other health problems. What’s worse is that the effects of poor quality sleep can, in turn, further disrupt […]
Inrebic (Fedratinib) receives FDA Approval for Myelofibrosis
The First New Treatment in Nearly a Decade for MF Patients INREBIC provides new, once-daily oral option for patients affected by rare bone marrow cancer SUMMIT, N.J.–(BUSINESS WIRE)–Celgene Corporation (NASDAQ: CELG) today announced the U.S. Food and Drug Administration (FDA) has approved INREBIC® (fedratinib) for the treatment of adult patients with intermediate-2 or high-risk primary or […]
Chronic Pain in Over 50 percent of MPN Cancer patients
Part 4 in a New Series: “Addressing MPN Symptoms” Prevalence of Chronic Pain and High-Impact Chronic Pain in Cancer Survivors in the United States Jiang C, Wang H, Wang Q, Luo Y, Sidlow R, Han X. Prevalence of Chronic Pain and High-Impact Chronic Pain in Cancer Survivors in the United States. JAMA Oncol. Published online June […]
Targeted therapies for Myeloproliferative Neoplasms MPNs
Abstract The discovery of JAK2V617F and the demonstration that BCR-ABL-negative myeloproliferative neoplasms (MPNs) are driven by abnormal JAK2 activation have led to advances in diagnostic algorithms, prognosis and ultimately also treatment strategies. The JAK 1/2 inhibitor ruxolitinib was a pivotal moment in the treatment of MPNs, representing the first targeted treatment in this field. Despite a […]
Nutrition and Diet May Reduce Chronic Inflammation while Improving Symptom Burden in MPN Patients
Part 3 in a New Series: “Addressing MPN Symptoms” Nutrition for MPN Patients We know diet plays a role in inflammation. Chronic inflammation may be an important driving force for clonal evolution and disease progression in myeloproliferative neoplasms (MPNs), essential thrombocythemia (ET), polycythemia vera (PV), and myelofibrosis (MF). So with that in mind, eating a healthy, […]
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