Pain in Your Big Toe?… Uric Acid Might Be the Culprit “pearls of wisdom” by the late Dr. Gilbert For your information re Uric Acid in MPN: Uric acid is a by-product of the metabolism of nucleoproteins(opens in new tab). These are molecules that arise from DNA and RNA released by cells when they die. Patients with […]
Questions to Ask your Doctor for a PV Appointment
By David Wallace Updated September 10, 2026 The most useful questions to ask your doctor about polycythemia vera cover your diagnosis, blood count goals, symptoms, treatment choices, and what to do between visits. Bring a short written list, start with your biggest concerns, and leave with a plan you understand. Our new Polycythemia Vera Guide […]
PV For Newbies – A Patient’s Perspective
Publisher’s Update – April 2026 This article was originally published in 2015 and remains a helpful overview for newly diagnosed PV patients. One important treatment update: since publication, the FDA has approved Besremi (ropeginterferon alfa-2b) for polycythemia vera. Besremi is a next-generation, long-acting interferon administered every two weeks and is the first interferon specifically FDA-approved […]
The Fleischman Lab Continues Investigating the Role of Inflammation in MPN
2015 MPN Research Update by Dr. Angela Fleischman We are continuing to work on the role of inflammation in MPN. The human immune system turns on the immune response when it recognizes invaders such as bacteria or viruses by producing inflammatory proteins, also called cytokines. Cytokines are helpful to fight infection but if the immune […]
