by David Wallace and Lou Ann Donovan Chronic inflammation is increasingly understood as a significant factor in the progression of many diseases, including Alzheimer’s and myeloproliferative neoplasms (MPNs), a group of blood cancers[1][2]. Myeloid blood cells, which are overproduced in MPNs, have been associated with Alzheimer’s disease, suggesting a link between these conditions[3]. Emerging evidence […]
Phase 3 Clinical Trial for Polycythemia Vera
Unfortunately for some polycythemia vera (PV) patients, current treatment options may not be fully effective or well-tolerated and may cause serious side effects. But a promising investigational treatment is currently being clinically evaluated. Rusfertide, also known as PTG-300, is an investigational new drug designed to slow the release of iron into the bone marrow. The […]
Transforming MPN Research Through Personal Experience
Part 1 in our new “Rising Stars” series featuring – Dr. Tyler Parsons Written by Heidi Cascarano and David Wallace Early Blood Clot Mysteries Like many MPN patients, Tyler’s journey to diagnosis was a long and winding road, marked by mysterious symptoms that remained unexplained for years. For Tyler, these symptoms took the form of […]
Promising New Gene Target to Combat Blood Cancer
A group of biomedical researchers from around the world, including Dr. Alexander Bick at Vanderbilt University Medical Center, have developed a new technique called PACER to measure the growth rate of abnormal blood stem cells. This breakthrough could help doctors reduce their patients future risk of blood cancer. Why This Matters: The Importance of Understanding […]
9 Tips for Reducing Risks of Thrombosis in MPNs
by David Wallace Understanding Thrombosis in MPN Patients Myeloproliferative neoplasms (MPNs) are a group of chronic blood cancers that affect the normal functioning of blood cells. People living with MPNs, such as polycythemia vera (PV), essential thrombocythemia (ET), and myelofibrosis (MF), have an increased risk of developing blood clots, or thrombosis. Thrombosis can lead to […]
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