Publisher’s Introduction by David Wallace After experiencing my own “unpleasant….putting it kindly” tango with Poly, I transitioned through various stages of grief and have seen other patients travel a similar path over the last few years. Rarely have I seen a newly diagnosed patient jump in full bore with both feet, wet behind the ears […]
Positive Correlation seen between JAK2V617F allele burden and thrombotic mechanisms activation in Polycythemia Vera and Essential Thrombocythemia patients
JAK2V617F allele burden is associated with thrombotic mechanisms activation in patients with Polycythemia Vera and Essential Thrombocythemia Abstract The clinical courses of polycythemia vera (PV) and essential thrombocythemia (ET) are characterized by thrombohemorrhagic diathesis. Several groups have suggested an association between JAK2V617F mutation and thrombosis. We hypothesized a relationship between JAK2V617F allele burden, cellular activation […]
23andMe Ordered by the FDA to Halt Sales of Genetic Test
Google backed Genetic Test Maker 23andMe told to Halt Sales by the Food and Drug Administration (FDA) As most readers know, 23andMe offered genetic testing for free to further research for MPN patients. A noble gesture indeed. I readily participated and found the highly detailed report very thought provoking, but perhaps “missing the mark” in […]
The American Society of Hematology (ASH) Annual Meeting and Exposition 2013
2013 ASH Annual Meeting and Exposition- KEY ABSTRACTS for Myeloproliferative Neoplasms December 7-10, 2013 – Ernest N. Morial Convention Center, New Orleans, LA Myeloproliferative Neoplasms Absracts Frequent Mutations in the Calreticulin Gene CALR in Myeloproliferative Neoplasms The Genomic Landscape of Myeloproliferative Neoplasms: Somatic Calr Mutations in the Majority of JAK2-Wildtype Patients Increased Platelet Thrombus Formation Under Flow […]
Medical scientists in Melbourne invent novel approach worldwide to Cure Leukemia
Combo Blood Cancer Treatment Attacking JAK2 Protein – A Possible Approach to Curing Leukemia Australian medical scientists have discovered a new approach which is regarded as the landmark to kill blood cancer cells for treating a large number of aggressive adult and childhood leukemia, Melbourne’s Peter MacCallum Cancer Centre said via the Friday’s media release. The report […]
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