Moshe Talpaz 1, Jean-Jacques Kiladjian 2 – Received: 14 February 2020 / Revised: 15 June 2020 / Accepted: 25 June 2020 © The Author(s) 2020. This article is published with open access Abstract Myeloproliferative neoplasm (MPN)-associated myelofibrosis (MF) is characterized by cytopenias, marrow fibrosis, constitutional symptoms, extramedullary hematopoiesis, splenomegaly, and shortened survival. Constitutive activation of […]
Protagonist Therapeutics early Phase 2 results for Polycythemia Vera Treatment Encouraging
Protagonist Therapeutics Announces Initial Phase 2 Results with Hepcidin Mimetic PTG-300 in the Treatment of Polycythemia Vera PTG-300 treatment demonstrates robust clinical response and provides clinically meaningful dose related control of hematocrit values on individual patient basis Results to be presented today by Ronald Hoffman, M.D., Director of the Myeloproliferative Diseases Program at The Icahn […]
Phyllis George dies from Polycythemia Vera complications
The MPN Community needs a Celebrity Spokesperson to bring awareness of our “Rare Blood Disease” by David Wallace I’m saddened to hear that former Kentucky first lady and Miss America, Phyllis George passed away from a “rare blood disease” at 70. She was a true pioneer in the TV broadcast industry, as the first woman […]
Coping with COVID-19
Easy Ways to Stay Calm by Lou Ann Donovan How Are You Coping with the Coronavirus Pandemic? The COVID-19 pandemic has brought many changes in how we live our lives now. It has brought uncertainty, changes to daily routines, financial concerns and social isolation. You may be worrying about getting sick or what the future […]
The New WHO classification for Essential Thrombocythemia calls for revision of available evidences
Abstract In the 2016 revised classification of myeloproliferative neoplasms pre-fibrotic primary myelofibrosis (pre-PMF) was recognized as a separate entity, distinct from essential thrombocythemia (ET). Owing that the majority of cases falling in the pre-PMF category were previously diagnosed as ET, one may question about the need to re-evaluate the results of epidemiologic, clinical, and molecular […]
NAC N-acetylcysteine Supplement may benefit MPN patients
by Deb Wesloh N-acetylcysteine (NAC) supplement has shown to have Antioxidant and Anti-inflammatory Properties Polycythemia vera, essential thrombocythemia, and myelofibrosis make up a class of blood cancers called myeloproliferative neoplasms, or MPNs. MPNs are characterized by the overproduction of red or white blood cells or platelets in the bone marrow. MPNs increase the risk of […]
Ocular Manifestations in Patients with Philadelphia Negative Myeloproliferative Neoplasms
Abstract: The major complications of Philadelphia‐negative (Ph‐Negative) myeloproliferative neoplasms (MPNs) are thrombosis, haemorrhage and leukemic transformation. As systemic and haematological diseases, MPNs have the potential to affect many tissues and organs. Some complications lead to the diagnosis of MPNs, but other signs and symptoms are often misdiagnosed or neglected as a sign of MPN disease. […]
Suffering from Signs and Symptoms of Polycythemia Vera?
Thrilled for Polycythemia Vera (PV) Diagnosis! Publisher’s Note (David Wallace): It’s rare that I will accept an anonymous patient story, just one other in 7 years. Starting back in October 2019, a gentleman who found PV Reporter at the top of a google search, reached out offering to share a “summary” of his story. We […]
MPN Facebook Group Leader, Patient Advocate Spotlight
Tips on Living with MPN – Reflections on 2020 by Christine Kennedy As the New Year is under way, its a time of reflection. MPN are an evolving disease. The difference in the years of running MPN groups has shown in what were arguments into basic knowledge of diagnoses. The arguments of diagnoses have settled […]
The AACR-MPM Oncology Charitable Foundation Announces First Grants to Support Transformative Cancer Research
PHILADELPHIA, PA and CAMBRIDGE, MA – Two grants for research that could transform cancer therapies have been funded through an innovative partnership between the American Association for Cancer Research (AACR) and MPM Capital through its management of the UBS Oncology Impact Fund (OIF). This unique grant program allows investigators who can make a significant impact […]
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