The following abstract involved the work of Dr Ron Hoffman, the principle investigator (PI), senior member of the MPN group at Mt Sinai Hospital in New York City as well as the PI of the MPN-RC. Xiaoli Wang, Phd, performed all of the lab work. Dr John Mascarenhas was my point of contact for this […]
Heidi’s MPN Story – An Increasing Trend in Patient Advocacy
by Heidi Cascarano “Watch and Wait…” What other cancer, in the 21st century, is so misunderstood that your local doctor will struggle to diagnose you, possibly tell you he has a few other patients with it, then advise you to do nothing but get a therapeutic phlebotomy and take a baby aspirin? You get online […]
An Opportunity to improve measurement of health related quality of life symptoms using MPN Patient reported outcomes
A Patient’s Perspective – Methods to Improve MPN Research by Collecting data and Blood test results from Patients by David Wallace As a PV patient, my treatment has run a wide spectrum during the last 6 years. Starting with phlebotomy only, Hydroxyurea (short time frame), Pegasys (nearing 2 years) and now the “cutting edge combo” […]
Concomitant JAK2 V617F-positive PV and BCR-ABL-positive CML with ruxolitinib and dasatinib
Citation: Blood Cancer Journal (2015) 5, e351; doi:10.1038/bcj.2015.77 Published online 2 October 2015 The combination of ruxolitinib and dasatinib was safe and effective in the treatment of concomitant PV and CML in this patient A Zhou1, E M Knoche1, E K Engle1, D A C Fisher1 and S T Oh1 1Division of Hematology, Washington University School of Medicine, St Louis, MO, USA […]
September is Blood Cancer Awareness Month
by David Wallace MPN Awareness for Blood Cancers in September Two quick items for news update: September is Blood Cancer Awareness Month, this is our time to promote MPN – Blood Cancer Awareness….be sure to post one of the many excellent images floating around on your Facebook profile (MPN Research Foundation and LLS have some […]
MPN Clinical Trial Highlights for Summer 2015
by mpdsupport.org Clinical Trials for MPNs are on the Rise! If you have MF, PV or ET but don’t need medication now, you may think that clinical trials don’t matter to you. But that could change, at which point you may want to review your options. Thankfully, over the past years the interest in developing […]
In Support of a Patient-Driven Initiative and Petition to Lower the High Price of Cancer Drugs
by David Wallace Be sure to watch the video of Dr Ayalew Tefferi, from Mayo Clinic, as he explains the initiative. Click below for the article. Source: In Support of a Patient-Driven Initiative and Petition to Lower the High Price of Cancer Drugs – Mayo Clinic Proceedings As a cancer patient who takes a cocktail […]
Discovery Could Boost New Therapies for Myeloproliferative Neoplasms
Researchers have discovered a way to potentially make drugs more effective at treating certain blood cancers. Source: Discovery Could Boost New Therapies for Myeloproliferative Neoplasms | Memorial Sloan Kettering Cancer Center
New blood cancer drug reaches cells hiding in bone marrow
A new drug aimed at dormant cancer stem cells that hide in the hypoxic zones of bone marrow that most other drugs can’t reach is currently in 5 clinical trials. Source: New blood cancer drug reaches cells hiding in bone marrow – UPI.com
Gout in MPN Patients Explained
Pain in Your Big Toe?… Uric Acid might be the Culprit “pearls of wisdom” by the late Dr. Gilbert, courtesy of mpdsupport.org For your information re Uric Acid in MPN: Uric acid is a by-product of the metabolism of nucleoproteins. These are molecules that arise from DNA and RNA released by cells when they die. Patients with […]
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