September Blood Cancer Awareness Month Spotlight by David Wallace David Wallace, your host with PV Reporter, talks to fellow PV patient advocate Diane Rose about living with Polycythemia Vera. Diane shares her patient story as we talk about how she was diagnosed, treatment, ET shifting to PV, being your own advocate, fear of needles and […]
Differential cytokine network profile in Polycythemia Vera and Secondary Polycythemia
Authors: Maira da Costa Cacemiro, Juçara Gastaldi Cominal, Maria Gabriela Berzoti-Coelho, Raquel Tognon, Natalia de Souza Nunes, Belinda Simões, Ítalo Sousa Pereira, Daniela Carlos, Lucia Helena Faccioli, Lorena Lobo de Figueiredo-Pontes, Fabiani Gai Frantz & Fabíola Attié de Castro Scientific Reports volume 10, Article number: 7032 (2020) Abstract Polycythemia vera (PV) is a clonal disorder resulting from neoplastic transformation of hematopoietic stem cells, while secondary polycythemia (SP) is a disease characterized by increased absolute […]
Immunotherapy in Myeloproliferative Diseases
by Lukas M. Braun 1,2 and Robert Zeiser 1,3,4,5,* 1 Department of Medicine I, Medical Center—University of Freiburg, Faculty of Medicine, University of Freiburg, 79106 Freiburg, Germany; lukas.braun@uniklinik-freiburg.de 2 Faculty of Biology, University of Freiburg, 79104 Freiburg, Germany 3 German Cancer Consortium (DKTK) Partner Site Freiburg, German Cancer Research Center (DKFZ), 69120 Heidelberg, Germany 4 […]
PTG-300 Hepcidin Mimetic Receives FDA Orphan Drug Designation for Treatment of Polycythemia Vera
NEWARK, Calif., June 17, 2020 /PRNewswire/ — Protagonist Therapeutics, Inc. (Nasdaq: PTGX) today announced that the U.S. Food and Drug Administration (FDA) has granted Orphan Drug Designation for PTG-300 for the treatment of polycythemia vera. PTG-300 is an injectable synthetic peptide mimetic of the natural hormone hepcidin currently in clinical development for the treatment of polycythemia vera and hereditary hemochromatosis. “Receiving […]
MPN Hub Launches Open Access Resource
by David Wallace The MPN Hub is an “open-access” online resource, dedicated to providing balanced, credible, and up-to-date medical education in MPN. The aim is to enhance knowledge in MPN, through the multichannel dissemination of global advances related to their classification, diagnosis, treatment, and management. The MPN Hub shares new data, evidence-based articles, therapy approvals, […]
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