by David Wallace The MPN Hub is an “open-access” online resource, dedicated to providing balanced, credible, and up-to-date medical education in MPN. The aim is to enhance knowledge in MPN, through the multichannel dissemination of global advances related to their classification, diagnosis, treatment, and management. The MPN Hub shares new data, evidence-based articles, therapy approvals, […]
MPN Specialist Explains PTG-300 and Clinical Trial for PV Patients
by David Wallace Hepcidin Mimetic PTG-300 Promising Treatment for PV How does PTG-300 work to reduce or eliminate the need for phlebotomy in PV? How does iron deficiency play a role in polycythemia vera? What are the goals of this treatment? Leading MPN expert, Dr. Srdan Verstovsek, from MD Anderson Cancer Center, interviews with David […]
Fedratinib newly approved treatment for Myelofibrosis patients
Moshe Talpaz 1, Jean-Jacques Kiladjian 2 – Received: 14 February 2020 / Revised: 15 June 2020 / Accepted: 25 June 2020 © The Author(s) 2020. This article is published with open access Abstract Myeloproliferative neoplasm (MPN)-associated myelofibrosis (MF) is characterized by cytopenias, marrow fibrosis, constitutional symptoms, extramedullary hematopoiesis, splenomegaly, and shortened survival. Constitutive activation of […]
Protagonist Therapeutics early Phase 2 results for Polycythemia Vera Treatment Encouraging
Protagonist Therapeutics Announces Initial Phase 2 Results with Hepcidin Mimetic PTG-300 in the Treatment of Polycythemia Vera PTG-300 treatment demonstrates robust clinical response and provides clinically meaningful dose related control of hematocrit values on individual patient basis Results to be presented today by Ronald Hoffman, M.D., Director of the Myeloproliferative Diseases Program at The Icahn […]
Phyllis George dies from Polycythemia Vera complications
The MPN Community needs a Celebrity Spokesperson to bring awareness of our “Rare Blood Disease” by David Wallace I’m saddened to hear that former Kentucky first lady and Miss America, Phyllis George passed away from a “rare blood disease” at 70. She was a true pioneer in the TV broadcast industry, as the first woman […]
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