Two MPN Clinical Trials Progress – Phase 3 Polycythemia Vera Study and Phase 2 Myelofibrosis Study There are dozens of clinical trials at various stages of progression for Polycythemia Vera, Essential Thrombocythemia and Myelofibrosis. Some are in the recruiting stage, others still active and the balance have been completed. Both of these trials will be […]
Bone & Joint Pain in MPN Patients Explained
Bone and Joint Pain in Myeloproliferative Neoplasms (MPNs): Understanding the Connection by David Wallace Bone and joint pain can be a common, yet often overlooked, symptom in patients with myeloproliferative neoplasms (MPNs). While some cases are attributed to conditions such as arthritis or gout, others may be linked directly to the disease itself, particularly in […]
Jane Murray’s MPN Story
A Moving Video Account of Jane’s Pre-diagnosis MPN Medical Mishaps After listening to Jane’s video presentation, I was deeply moved by her story and asked if I could post it, along with her comments from an online forum. Thankfully, she accepted the post invite graciously and without hesitation. She presented at the MPN Awareness day on […]
Thank you for a most successful launch and join the PV Reporter mailing list!
For those who have yet to sign up for the PV Reporter mailing list, please consider doing so. I want to share our First Newsletter Update. Here is the Newsletter in it’s entirety: Successful Launch! Introduction: PV Reporter was created by David Wallace, an aspiring web designer, publisher, writer, and chief bottle washer. […]
JAK2 p.V617F detection and allele burden measurement in peripheral blood and bone marrow aspirates in patients with myeloproliferative neoplasms
Key points The sensitivity and specificity of detecting the JAK2 p.V617F mutation in peripheral blood are both 100% compared to bone marrow. The JAK2 p.V617F allele burden measured in peripheral blood is equivalent to that in bone marrow aspirate (R2=0.991; P<0.0001). See the Abstract Here
